Emergency Medicine Perspectives of Students – World

EM perspectives of students - world

Dear EM family,

The International Emergency Medicine Education Project (iem-student.org) has completed three years. As you may know, the iEM Education project aims to promote Emergency Medicine and provides copyright-free resources to students and educators around the world. Now we have reached more than 200 countries. We would like to thank again our contributors. Without them, such a project would not be possible. This experience has shown us once again how passionate our international EM community is to help and teach each other.

In May 2021, we started the fourth year of this journey. To celebrate, we are pleased to announce alive activity series, Emergency Medicine Perspectives of Students Around the World. Our guests for the second session are Maryam Zadeh from Canada, Nawaf Alamri from Saudi Arabia, and Rebeca Barbara from Brazil, who are the leaders of the International Student Association of Emergency Medicine.

Together, we can understand the experiences and needs of medical students from different backgrounds and discuss potential solutions.

Here are the video and audio records of this session. 

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A Simplified Guide into Emergency Medicine – UK

A Simplified Guide into Emergency Medicine

The great thing about going into emergency medicine (EM) is that it allows entry into the program at various points of your career. So whether you know right off the bat following your two foundations years or whether it takes you a couple of years to make a choice, there is a straight pathway into the speciality (give or take a bit more competition!).

Acute care common stem (ACCS)

The most common entry route into emergency medicine from your foundation years is through the Acute care common stem (ACCS). This will be a 3-year training program and so becomes your CT1-3 years. This will comprise four six-month rotations in Intensive care medicine (ICM), emergency medicine (EM), anesthesia, and acute medicine (AM). Following this, there will be a one-year focus on EM and pediatric emergency medicine (PEM). In terms of examinations, the major ones that need to be completed are the MCEM Part A before the CT3 year and the MCEM Parts B and C before progressing to higher specialty training (ST4).

Defined route of entry into EM training (DRE-EM)

If one doesn’t do the ACCS and decides they want to enter EM in their ST3 year, this can be done view the DRE-EM. For the two years before entry into the DRE-EM at ST3, you need to have a minimum of 2 years of experience in substantive EM posts (which exclude any done during your foundation years). In addition, one of these posts needs to have been in the UK in the previous four years. Examples of such posts could be a core trainee level in an ACCS specialty (anesthesia, EM, ICM, AM), which at the end of the pathway would give you a Certificate of Completion of Training (CCT), or in core surgical training, which would give you a Certificate of Eligibility for Specialist Registration by the combined program route (CESR CP). Your ST3 year following acceptance into the DRE-EM can take 18 to 24 months, depending on how quickly competencies are met to enter ST4. 
 
Before entry into their ST4 years, trainees will be required to have completed the EM specialty-specific examinations before progressing into ST4:
• MCEM Part A or MRCS (Latter for DRE-EM trainees only) 
• MCEM Parts B and C
 
At the end of this training, all trainees will be required to complete the FCEM exit example before their awarded their CCT.  

Higher Specialty training (HST) in EM

This is one of the pathways into EM that can be taken following CT3/ST3. Entry at this point is by a selection through a national recruitment process. From this point, HST trainees can also apply for subspecialty training posts, such as PEM or prehospital emergency medicine. This training post doesn’t have to be full-time (i.e., done over two years instead of one year).

This simplified pathway can be seen in the figure below.

However, your route into EM isn’t always straightforward; you might be considering taking a detour, so it’s important to remember that there are backways into EM as well, and not everything will have been covered here! So make sure to check out the ACCS 2021 curriculum guide or the RCEM website for more details.

Further Reading

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Question Of The Day #62

627.15 - Figure 15 - lentiform epidural hematoma in the right hemisphere

Which of the following is the most likely diagnosis for this patient’s condition?

This patient presents to the Emergency Department after a high-speed motor vehicle accident.  On examination, he is tachycardic, mildly tachypneic, and has an altered mental status (somnolent).  The first step in evaluating this trauma patient involves the primary survey.  The primary survey is also known as the “ABCDEFs” of trauma.  This stands for Airway, Breathing, Circulation, Disability, Exposure, and FAST exam (Focused Assessment with Sonography in Trauma).  Each letter should be assessed in alphabetical order to avoid missing a time sensitive life-threatening condition.  The primary survey should be conducted prior to taking a full history.

After the primary survey, a more detailed physical exam (secondary survey) is conducted, followed by interventions and a focused patient history.  A noncontrast CT scan of the head is a reasonable test for this patient given his significant mechanism of injury and altered mental status on exam.  The CT scan shows a hyperdense (white) biconvex area on the right side of the brain.  This white area indicates the presence of fresh blood on the CT scan.  Keep in mind that CT scans are read as if you are looking up from the patient’s feet to their head.  This means left-right directionality is reversed.  See image below.

A hyperdense area with a sickled or crescent-shaped appearance would indicate an acute subdural hemorrhage (Choice A).  This is caused by tearing of the cerebral bridging veins.  Hyperdense areas throughout the brain tissue itself would indicate an intraparenchymal hemorrhage (Choice B).  Hyperdense areas around the sulci of the brain and a starfish appearance would indicate a subarachnoid hemorrhage (Choice D). Subarachnoid bleeding is caused by rupturing of a brain aneurysm or an arteriovenous (AV) malformation.  Subarachnoid bleeding can also be associated with trauma. 

This patient’s CT image shows an epidural hemorrhage (Choice C), indicated by the biconvex lens shaped area of blood.  This is caused by tearing of the middle meningeal artery.  Treatment of all types of intracranial bleeding involves general supportive care, airway management (i.e., endotracheal intubation for GCS < 8), elevating the head of the bed to 30 degrees to lower intracranial pressure (ICP), managing pain and sedation (lowers ICP), blood pressure maintenance (goal SBP <140mmHg), reversal of coagulopathy, neurosurgical evaluation for possible operative intervention, and providing ICP lowering treatments (mannitol or hypertonic 3% NaCl) when concerned about elevated ICP or brain herniation.

References

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Generating research question

Generating research question

In this educational series, iEM Education Project interviewed Prof. Fikri Abu-Zidan, a world-renowned expert and researcher on trauma, POCUS, and disaster management. He shares his 40 years of experience as a clinical researcher with the young generation of doctors.

The series name is FUNDAMENTALS OF RESEARCH IN MEDICINE and will include various aspects of research. We hope you will enjoy listening to the advice of Prof. Abu-Zidan.

The 4th episode is “Generating research question”

Professor Fikri Abu-Zidan, the head of the Trauma Group at United Arab Emirates University, is an Acute Care Surgeon who graduated (MD) from Aleppo University (Syria) in 1981 and was awarded the FRCS, Glasgow, Scotland in 1987.  He achieved his PhD in Trauma and Disaster Medicine from Linkoping University (Sweden) in 1995 and obtained his Postgraduate Diploma of Applied Statistics from Massey University (New Zealand) (1999). His clinical experience included treating war injured patients during the Second Gulf War (1990). He has been promoting the use of Point-of-Care Ultrasound (POCUS) for more than thirty years in which he is a World Leader. Furthermore, he is an international expert on trauma experimental methodology developing novel clinically relevant animal models. Establishing experimental surgical research in Auckland University, New Zealand, has led to a strong successful PhD Program.  

He has made major contributions to trauma management, education and research in Kuwait, Sweden, New Zealand, Australia and UAE.  He authored more than 415 publications, presented more than 600 invited lectures and abstracts, and received more than 40 national and international awards. He is serving as the Statistics Editor of World Journal of Emergency Surgery and European Journal of Trauma and Emergency Surgery. 

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Journal Club 10-04-21 : Health Equity, Medical Tourism, and Maternal Mortality in LMICs

Welcome back! The first GEMS LP  journal club of the season took place on October 4th, 2021. During each meeting, we discuss a journal article, a global health clinical topic, and a book chapter from one of two books: An Introduction to Global Health Delivery by Joia Mukherjee or Reimagining Global Health: An Introduction by Paul Farmer, Jim Yong Kim, Arthur Kleinman, and Matthew Basilico.

The goal of journal club is to expose our mentees to fundamental global health concepts and their applications in the real world. Having a diverse cohort of participants allows for lively and engaging discussion based on each participants’ life experiences. Below is a summary of each section presented at journal club. Be sure to join us at our next meeting, taking place November 8th, 2021.

Many of the global health disparities that exist today are a result of centuries of exploitation of developing countries that can trace its roots to the slave trade. As slavery ended in the 19th century, the extraction of people was replaced with the extraction of resources as European nations divided up Africa amongst themselves. By the 20th century, centuries of exploitation had robbed newly independent countries of the resources needed to provide healthcare for their citizens. Newly liberated countries came to rely on Western monetary institutions for loans, which often came with strings attached. Loans from the World Bank and the International Monetary Fund limited the amount of public expenditures on vital healthcare infrastructure, medication, and personnel. Healthcare in developing countries was further undermined by the neoliberal policies promoted by Western countries beginning in the 1980s. Developing countries were compelled to fund healthcare through above-cost user fees, which reinforced unequal access to care and widened healthcare inequality. The neoliberal approach also championed the concept of sustainability, which focused on low-cost preventative care instead of treatment. By the 1990s, this approach had led to widening healthcare inequity between the developed and developing worlds.

An alternative approach advocated for the right to health of every individual as envisioned in the Universal Declaration of Human Rights. The 1978 Alma Ata Declaration proposed that the fulfillment of these rights belongs to the international community through international collaboration. The past several decades has seen an increasing movement towards this idea and away from one based on economics. An example of this would be the recognition in the 1990s that citizens of developing nations with HIV are inherently as deserving of treatment as those from developed nations. By taking an approach rooted in human rights, the international community was able to lower the cost of HIV medication and provide treatment for patients in the developing world.

Discussion Questions:

·Reflect on prior medical service trips you may have gone on or may be offered by your university. In what ways do these trips reflect the legacy of colonialism? How can we “de-colonize” global health in medical education? 

·Should all medical interventions in lower-income and developing countries be “sustainable”? 

Medical tourism is a modern practice in healthcare that is exacerbating global health inequity. For centuries, people of higher socioeconomic classes commonly visited higher developed countries to receive care for their medical ailments. Their journeys are much more expensive than an ordinary citizen could afford but with the advent of air travel and a rapid development of the middle class with a larger share of disposable income, many more people are travelling for medical services today than ever before. The propagation of medical tourism is exacerbating the divide in quality of care in developing countries. As private hospitals primarily attract international patients, they attract more doctors with higher salaries and benefits paid for by medical tourists’ bills. This develops a positive feedback loop that continues to neglect the care of the poorest patients who need the most advanced care and rely on public hospital systems that are already overburdened. Rather than focusing on bettering the care of public hospitals and working for the native populations, private hospital systems and governments encouraging medical systems are further dividing the health gap between socioeconomic classes and contributing to health inequity.

Discussion Questions:

What are some ethical issues developed by private healthcare systems motivated by financial incentives?

• How can medical professionals in our country educate patients about the risks of medical tourism?

 

Global health disparity is apparent in the care of pregnant individuals, with 94% of all maternal deaths occurring in low and lower-middle-income countries. A leading cause of maternal and perinatal mortality in these regions is hypertensive disorders of pregnancy, especially pre-eclampsia and its spectrum of diseases. Crucial to the screening and diagnosis of these disorders are regular antenatal care and assessment of risk factors, such as advanced maternal age, obesity, diabetes, and existing hypertension. For pre-eclampsia and eclampsia, the WHO has released evidence-supported recommendations for both preventative measures, such as calcium supplementation in areas with low intake, and treatment, such as using magnesium sulfate over other anticonvulsants. In low resource settings, some of the barriers that hinder the care of pregnant individuals with hypertensive disorders are a shortage of specialty-trained healthcare workers, inadequate transportation to healthcare facilities, limited antenatal care, and traditional cultural practices. While much work still needs to be done in tackling many of these challenges, especially in improving basic obstetric emergency treatment at primary community settings, innovative strategies such as task-shifting to train community health workers (CLIP initiative) in providing regular antenatal care and community cost-sharing schemes to eliminate financial barriers to obstetric care in Mali have been shown to have positive outcomes.

Discussion Questions:

· What other non-health related barriers may contribute to maternal mortality?

· What roles can emergency services/emergency medicine physicians play in improving the outcome of obstetric emergencies?

Wrap up!

As you can imagine, our mentees had a wonderful discussion surrounding these three topics! We are thrilled to be able to present a brief summary of their work here. Please stay tuned for details about our upcoming meetings, the next of which is taking place November 8th, 2021.  Connect with us through one of our contact options listed below if you are interested in attending!

Thank you to our authors and presenters!

Picture of Brian Elmore, MS4

Brian Elmore, MS4

Medical University of South Carolina

Picture of Jai Shahani, MS2

Jai Shahani, MS2

Rutgers New Jersey Medical School

Picture of Luxi Qiao, MS4

Luxi Qiao, MS4

Washington University School of Medicine

Sources:

  • Mukherjee, Joia. “Chapter 1: The Roots of Global Health Inequity.” An Introduction to Global Health Delivery: Practice, Equity, Human Rights, Oxford University Press, New York, NY, 2018.
  • Mutalib, Nur & Ming, L C & Yee, Esmee & Wong, Poh & Soh, Yee. (2016). Medical Tourism: Ethics, Risks and Benefits. Indian Journal of Pharmaceutical Education and Research. 50. 
  • 261-270. 10.5530/ijper.50.2.6.
  • http://ijper.org/sites/default/files/10.5530ijper.50.2.6.pdf
  • WHO. Maternal mortality evidence brief, 2019.
  • WHO. WHO recommendations for prevention and treatment of pre-eclampsia and eclampsia, 2011.
  • Fournier P, Dumont A, Tourigny C, Dunkley G, Drame S. Improved access to comprehensive emergency obstetric care and its effect on institutional maternal mortality in rural Mali. Bull World Health Organ 2009; 87: 30-8
  • von Dadelszen P, Vidler M, Tsigas E, Magee LA. Management of Preeclampsia in Low- and Middle-Income Countries: Lessons to Date, and Questions Arising, from the PRE-EMPT and Related Initiatives. Maternal-Fetal Medicine 2021; 3(2): 136-50.
  • Firoz T, Sanghvi H, Merialdi M, von Dadelszen P. Pre-eclampsia in low- and middle-income countries. Best Pract Res Clin Obstet Gynaecol 2011; 25: 537-48.
  • Milne F, Redman C, Walker J, et al. The pre-eclampsia community guideline (PRECOG): how to screen for and detect onset of pre-eclampsia in the community. BMJ 2005; 330: 576-80.

 

Keep in Touch:

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Question Of The Day #61

Which of the following is the most appropriate next step in management for this patient’s condition?

This patient arrives to the hospital after penetrating trauma to the right chest.  His initial examination reveals hypotension, tachycardia, tachypnea, and a low oxygen saturation.

All medical and trauma patients that arrive to the Emergency Department, especially those who are ill-appearing or with abnormal vital signs, should undergo the “ABCs”.  This is also known as the primary survey.  The primary survey aims to create a step-wise initial approach to patients where all life-threatening conditions are identified and treated early in the encounter with the patient.  The primary survey should be conducted prior to taking a full history.  In trauma patients, the primary survey is extended to include the “ABCDEFs”.  This stands for Airway, Breathing, Circulation, Disability, Exposure, and FAST exam.  Each letter should be assessed in alphabetical order to avoid missing a time sensitive life-threatening condition. 

Airway assessment involves checking for airway patency (clear voice, stridor, blood or vomitus in mouth, etc.) and applying cervical spine immobilization if needed.  Endotracheal intubation or a surgical airway may need to be placed during this step.  Breathing assessment involves auscultation of the lungs, checking the oxygen saturation, and providing supplemental oxygen to the patient if needed.  Abnormalities in the breathing exam (absent unilateral lung sounds, tracheal deviation, etc.) may prompt the placement of a chest tube or needle decompression.  It is during the breathing step that a pneumothorax, tension pneumothorax, or hemothorax is identified and treated.  Circulation assessment involves checking the heart rate and blood pressure, palpating all peripheral pulses, establishing IV access, and administering IV fluids or blood products.  It is during the circulation step that hemorrhage and shock is identified and controlled (pressure dressing applied to bleeding extremity wound, tourniquet applied to slow bleeding at amputated limb, etc.).  Disability assessment involves checking the patient’s neurologic status.  This involves calculating a GCS (Glasgow Coma Score), measuring the patient’s glucose level, and performing a focused neurologic exam.  Exposure involves removing all the patient’s clothes which may be obstructing view of other injuries.  This step involves rolling the patient to the lateral decubitus position to check the back and perineal areas for trauma.  The last step of the primary survey in trauma is the FAST exam (Focused Assessment with Sonography in Trauma).  The FAST exam is a quick sonographic exam that requires the practitioner to look at 4 anatomical areas for signs of internal injuries.  The 4 areas are the right upper abdominal quadrant, left upper abdominal quadrant, pelvis, and subxiphoid (cardiac) areas. 

The question stem provides information regarding the airway of the patient, which is stated to be patent.  The next step in the “ABCDEFs” should be evaluation of the ‘Breathing’.  Administration of packed red blood cells (Choice A) is considered part of the “Circulation” assessment.  Removing the patient’s clothes to evaluate for occult injuries (Choice C) is important, but the “Breathing” assessment should be performed prior to the patient’s “Exposure” step.  Performing a FAST exam (Choice D) is also an important part of the primary survey, but it should be performed after the “Breathing” step is completed.  Auscultation of both lungs (Choice B) is the best next step, as this is part of the “Breathing” step after the “Airway” assessment.  During this step, the patient should be given supplemental oxygen and evaluated for abnormal or absent unilateral lung sounds.  This is important as this patient is at risk for a large pneumothorax, tension pneumothorax, or hemothorax after his penetrating trauma.   

References

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Emergency Medicine Perspectives of Students – Africa

EM perspectives of students - africa

Dear EM family,

The International Emergency Medicine Education Project (iem-student.org) has completed three years. As you may know, the iEM Education project aims to promote Emergency Medicine and provides copyright-free resources to students and educators around the world. Now we have reached more than 200 countries. We would like to thank again our contributors. Without them, such a project would not be possible. This experience has shown us once again how passionate our international EM community is to help and teach each other.

In May 2021, we started the fourth year of this journey. To celebrate, we are pleased to announce live activity series, Emergency Medicine Perspectives of Students Around the World. Our guests for the first session are Adebisi Adeyeye from Nigeria, Jonathan Kajjimu from Uganda, and Mohamed Hussein from Egypt, who are Student Council Leaders of the African Federation for Emergency Medicine

Together, we can understand the experiences and needs of medical students from different backgrounds and discuss potential solutions.

Here are the video and audio records of this session. 

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Under the scorching sun – Heat Stroke Q&A

Under the scorching sun – Heat Stroke Q&A

Different parts of the world are experiencing extremes of temperature. Especially in the Middle East and Asia this time of the year, heatstroke is one of the commonest presentations in the emergency department (ED). Both developed and developing countries suffer from it.

Heatstroke can range from being mild to severe, and it can lead to multi-organ damage and eventually death, especially in cases not treated in time.

Heatstroke can present in various ways and may mimic other illnesses. In the ED, just like anything else, history is an essential part of management.

What is heatstroke and how does it occur?

The body functions well at a set temperature. When a person is present in extremes of temperature, dehydrated, or performs physical exertion in high temperatures, the thermoregulatory mechanism does not work effectively, causing overheating and body temperature to reach up to 40 degrees celsius. This change in body temperature, if not treated rapidly, causes different organs to deteriorate, as the organs function at the optimal temperature and a change from the normal causes their dysfunction.

Heatstroke is divided into two types – Classical or non-exertional heatstroke is common in children and the elderly who spend time outdoors in the heat and exertional heatstroke is seen in workers and soldiers who perform activities outdoors for long periods of time.

What are some risk factors that may increase the chances of developing a heat stroke?

Heatstroke can occur in almost anyone, but certain factors increase the risk, such as:

  • People of extremes of age and those who work outdoors during the daytime (eg – construction workers). 
  • Dehydration and exposure to high temperature with inadequate ventilation.
  • Certain medications such as antipsychotics, antidepressants, and diuretics etc.

How do the patients present to the ED?

The presentation of heatstroke may mimic many illnesses and history is one of the most important factors in making a decision. Here is the various presentations that can be related to heatstroke:

  • High body temperature >40 degrees celsius
  • Changes in behaviour
  • Changes in perspiration – skin would be dry and warm to touch 
  • Seizures
  • Symptoms of dehydration
  • Nausea and vomiting
  • Flushing of skin
  • Tachypnea and tachycardia
  • Headache
  • Coma

How to evaluate the patient?

The evaluation starts with taking a history from the patient or someone accompanying them. History of heat exposure increases the suspicion. You should also see:

  • Vitals signs and temperature monitoring, rectal if possible.
  • Cardiac monitoring – the monitor will show sinus tachycardia
  • Complete blood count (CBC), Reflo, Urea and Electrolytes, Liver and Kidney function, Lactate 
  • Creatine phosphokinase (CPK) levels

Management in the ED

  • Start with ABC’s – patients may present in a coma and may require intubation
  • Remove any excessive materials of clothing
  • Cool the patient with a cooling blanket
  • Fluid resuscitation – cold IV Fluids
  • The target temperature is 38.5 degrees celsius

Cooling Techniques

  • Cold exposure – Several techniques can be used such as cold water splashes/spraying, placing a fan, immersion in an ice bath, or cold water packs 
  • Dantrolene – A drug that reduces heat production in the body, has shown no effect in improving outcomes in patients with heatstroke and hence is not indicated.
  • Medications may be used for symptomatic relief. However, the gold standard management is rapid cooling using any of the above-mentioned methods.
689.3 - Figure 3. Waterproof matress and Cooling Unit

What complications can occur if the patient is not treated rapidly?

  • Coma
  • Seizures 
  • Electrolyte imbalance
  • Bleeding
  • Multi-organ damage
  • Neurological dysfunction 
  • ECG changes
  • Hypotension 

What are some of the differential diagnoses of heatstroke?

  • Drug ingestion and overdose
  • Meningitis
  • Malaria
  • Serotonin syndrome

How can we prevent heat stroke?

  • Public education and occupational health initiatives to spread awareness amongst the public and workers to protect themselves, stay hydrated at all times, and set duty and break hours during peak daytime.
  • Availability of rapid cooling equipment in emergency departments

References and Further Reading

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Question Of The Day #60

question of the day
Which of the following is the most likely cause for this patient’s condition? 

This first-trimester pregnant patient presents with generalized weakness, nausea, and vomiting.  She is hypotensive and tachycardic with no sign of urinary infection on the urinalysis.  The many ketones in the urine indicate the patient has inadequate oral nutrition and is breaking down muscle and adipose tissue for energy.  This is likely related to the persistent vomiting the patient is experiencing.  This patient has hyperemesis, a common condition in the first trimester of pregnancy that is caused by rising levels of beta-human chorionic gonadotropin (BHCG).  Treatment for this patient should include IV hydration and antiemetics.  Admission criteria for these patients includes intractable vomiting despite antiemetic administration, over 10% maternal weight loss, persistent ketone or electrolyte abnormalities despite rehydration, or uncertainty in the diagnosis. 

The fluid losses caused by vomiting in this condition result in hypovolemic shock (Choice B).  Distributive shock (Choice C) is caused by other conditions, like sepsis, anaphylaxis, and neurogenic shock.  A ureteral stone (Choice D) is unlikely as the patient does not report any abdominal, back, or flank pain.  The urinalysis also does not show any hematuria, which is a common sign of a ureteral stone.  Pyelonephritis (Choice A) can cause vomiting and septic shock which can result in hypotension and tachycardia.  However, there is no sign of infection in the urinalysis provided, no fever, and no back or flank pain.  The best answer is choice B.  

References

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Understanding Authorship

Understanding Authorship

In this educational series, iEM Education Project interviewed Prof. Fikri Abu-Zidan, a world-renowned expert and researcher on trauma, POCUS, and disaster management. He shares his 40 years of experience as a clinical researcher with the young generation of doctors.

The series name is FUNDAMENTALS OF RESEARCH IN MEDICINE and will include various aspects of research. We hope you will enjoy listening to the advice of Prof. Abu-Zidan.

The 3rd episode is “Understanding Authorship”

Professor Fikri Abu-Zidan, the head of the Trauma Group at United Arab Emirates University, is an Acute Care Surgeon who graduated (MD) from Aleppo University (Syria) in 1981 and was awarded the FRCS, Glasgow, Scotland in 1987.  He achieved his PhD in Trauma and Disaster Medicine from Linkoping University (Sweden) in 1995 and obtained his Postgraduate Diploma of Applied Statistics from Massey University (New Zealand) (1999). His clinical experience included treating war injured patients during the Second Gulf War (1990). He has been promoting the use of Point-of-Care Ultrasound (POCUS) for more than thirty years in which he is a World Leader. Furthermore, he is an international expert on trauma experimental methodology developing novel clinically relevant animal models. Establishing experimental surgical research in Auckland University, New Zealand, has led to a strong successful PhD Program.  

He has made major contributions to trauma management, education and research in Kuwait, Sweden, New Zealand, Australia and UAE.  He authored more than 415 publications, presented more than 600 invited lectures and abstracts, and received more than 40 national and international awards. He is serving as the Statistics Editor of World Journal of Emergency Surgery and European Journal of Trauma and Emergency Surgery. 

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Out of Proportion: Acute Leg Pain

Case Presentation

A 48-year-old male, with history of hypertension and diabetes and prior intravenous drug use (now on methadone) presents with acute onset right leg pain from his calf to the ankle, that woke him from sleep overnight. The pain has been constant, with no modifying or relieving factors. He hasn’t taken anything other than his daily dose of methadone. He hasn’t had any fevers or chills and denies any recent trauma or injuries.

Any thoughts on what else you might want to ask or know?

  • Any recent travel or prolonged immobilization?
  • Have you ever had a blood clot?
  • Are you on any blood thinners?
  • Have you used IV drugs recently?
  • Any numbness or weakness in your leg?
  • Any associated rash or color change?
  • Any back pain or abdominal pain? Any bowel or bladder incontinence?
  • Any recent antibiotics (or other medication changes)?
  • Have you ever had anything like this before?
[all of these are negative/normal]

Pause here -- what is your initial differential diagnosis looking like?

  • Deep vein thrombosis
  • Superficial vein thrombosis
  • Pyomyositis
  • Necrotizing fasciitis
  • Muscle sprain or tear
  • Arterial thromboembolism
  • Bakers cyst
  • Achilles tendonitis, Achilles tendon rupture

What are some key parts of your targeted physical exam?

  • VITAL SIGNS! [BP was slightly hypertensive, and he is slightly tachycardic, normothermic]
  • Neurologic exam of the affected extremity (motor and sensory)
  • Vascular exam of the affected extremity (femoral/popliteal/posterior tibialis/dorsalis pedis)
  • Musculoskeletal exam including ranging the hip, knee, ankle and palpating throughout the entire leg
  • Skin exam for signs of injury or rashes etc.
  • Consider a cardiopulmonary and abdominal exam, particularly the lower abdomen

On this patient’s exam, he was overall uncomfortable appearing and had slight tachycardia (110s, EKG shows normal sinus rhythm), normal cardiopulmonary exam, normal abdominal exam. He had a 2+ right femoral pulse and faintly palpable DP pulse that had a good biphasic waveform on doppler. His hip/knee/ankle all have painless range of motion. The compartments are soft in the upper and lower leg. He does have some diffuse calf tenderness and the medial aspect feels slightly cool compared to the contralateral side, but his foot is warm and well perfused. There isn’t any spot that is most tender. There is no rash, no crepitus, no bullae or bruising or other evidence of injury.

What diagnostic studies would you like to send?

  • CBC, BMP
  • CPK, lactate
  • DVT ultrasound?
  • Anything else?

What treatments would you like to provide?

  • Analgesia (mutli-modal)?
  • Maybe a bolus of IV fluids to help with the tachycardia?

The patient is having a lot of pain despite already getting NSAIDs, acetaminophen, and a dose of morphine. You decide to re-medicate the patient with more morphine and send him for DVT ultrasound. As soon as he gets back, he’s frustrated that you still haven’t treated his pain “at all” and he really does look uncomfortable and in a lot of pain.  You start to wonder if he’s faking it giving his history of IV drug use.

His DVT ultrasound comes back as normal. The lab work is also coming back and unrevealing. A normal CBC, metabolic panel, normal CPK, normal lactate. His pain is not really improving. You reexamine the leg, and the exam is unchanged. It really seems like his pain is out of proportion to the exam.

Pain is out of proportion to the exam should catch your attention every time. While we always need to keep malingering and less emergent causes for pain that seems to be more than expected in the back of our minds. But! Several emergent diagnoses have patients presenting in pain in a way that doesn’t fit what you can objectively identify as a cause. Diagnoses like compartment syndrome and mesenteric ischemia can be erroneously dismissed by emergency providers, and it is crucial you don’t just stop looking for the cause of pain out of proportion. In fact, it’s important you dig in deeper and rule out all potentially life and limb threatening causes.

In this case, the pain was recalcitrant to multiple doses of IV opiates and several other modes of treatment. The patient was getting so frustrated that he pulled out his IV and threatened to leave the ED. After talking with him further, he agreed to stay and a new IV was placed, more pain medication given, and a CTA with lower extremity run-off was performed, which showed the acute thrombus of the proximal popliteal artery, just below the level of the knee.

He was started on a heparin infusion and vascular surgery was consulted; the patient was admitted from the ED and taken for thrombectomy. No source of embolism was identified, and his occlusion was presumed to be thrombotic (most commonly from a ruptured atheromatous plaque leading to activation of the coagulation cascade), with particular attention to his history of diabetes and hypertension raising his risk for this. He had a fair amount of collateralization from other arteries around the occlusion, such that his foot wasn’t cold, and he had a doppler-able DP pulse. 

Remember

Go with your gut and don’t minimize pain that is out of proportion to the exam. Keep hunting for a reasonable explanation or you may miss a life or limb threatening cause of an atypical emergency presentation.

Further Reading

Deep Vein Thrombosis (DVT)

by Elif Dilek Cakal Case Presentation An 85-year-old woman, with a history of congestive heart failure, presented with right leg pain and swelling of 2

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Acute Mesenteric Ischemia

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Question Of The Day #59

question of the day
38 - atrial fibrillation

Which of the following is the most likely cause for this patient’s respiratory condition?

This patient presents to the Emergency Department with palpitations, generalized weakness, and shortness of breath after discontinuing all her home medications.  She has hypotension, marked tachycardia, and pulmonary edema (crackles on lung auscultation).  The 12-lead EKG demonstrates atrial fibrillation with a rapid ventricular rate.  This patient is in a state of cardiogenic shock and requires prompt oxygen support, blood pressure support, and heart rate control. 

Pulmonary embolism (Choice A) can sometimes manifest as new atrial fibrillation with shortness of breath and tachycardia, but pulmonary embolism initially causes obstructive shock.  If a pulmonary embolism goes untreated, it can progress to right ventricular failure, pulmonary edema, and cardiogenic shock.  This patient has known atrial fibrillation and stopped all her home medications.  The abrupt medication change is a more likely cause of the patient’s cardiogenic shock.  Dehydration (Choice D) and systemic infection (Choice D) are less likely given the above history of abruptly stopping home maintenance medications.  Untreated cardiac arrythmia (Choice B) is the most likely cause for this patient’s pulmonary edema and cardiogenic shock. 

The chart below details the categories of shock, each category’s hemodynamics, potential causes, and treatments.  

 

References

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